I read a lot of RSS feeds for work, blogging, and general interest. I used to use Google Reader for most of this before I had my iPhone. When the iPhone came out though I found that the iPhone reader was very difficult for me to read without my reading glasses (I have reached that point in life when I need to keep reading glasses close when I am going to do serious reading). When I read feeds on my laptop, I don’t mind using my glasses but if I am away from the computer and just trying to catch a quick update, reading glasses are a pain to deal with.
Since the Reader on the iPhone wouldn’t let me change fonts, I went with another service, Newsgator, for my needs. This required me to use their desktop app (or web app) as well. I still prefered Google’s Reader but the entire package put me ahead.